正高
E-Mail:723a0298723848b34510eb1ec1fd677528b7bf45c4fe90cd20e79ed4d959a72faea0f051d90db3c295f9a1b440ceaa2e46bff9db8bd2a5ccc949c0a665e419433669caf9afc15709a2281a5972947ce4f2bd206aa8feadee1cfbf5da0b54a5b33b64069f21ff0dcf2b803f5bd12daeeed6dea4672d74c527f79ceae6fb2e00be
Date of Employment:2014-09-03
School/Department:生物治疗全国重点实验室
Administrative Position:教授
Contact Information:chongchen@scu.edu.cn 实验室网站:https://www.chenliulab.org/
Status:在岗
Alma Mater:(美国)密切根大学-安娜堡分校
The Last Update Time: ..
[1] Mosaic loss of chromosome Y promotes leukemogenesis and clonal hematopoiesis.JCI Insight,2022.10.1172/jci.insight.153768
[2] SRT1720 inhibits the growth of bladder cancer in organoids and murine models through the SIRT1-HIF axis.ONCOGENE,2021
[3] An Epigenetic Mechanism Underlying Chromosome 17p Deletion–Driven Tumorigenesis.Cancer Discovery,2020
[4] Deletions linked to TP53 loss drive cancer through p53-independent mechanisms.Nature,2016
[5] MLL3 Is a Haploinsufficient 7q Tumor Suppressor in Acute Myeloid Leukemia.Cancer Cell,2014
[6] Cancer-associated IDH2 mutants drive an acute myeloid leukemia that is susceptible to Brd4 inhibition.GENES & DEVELOPMENT,2013
[7] Mammalian target of rapamycin activation underlies HSC defects in autoimmune disease and inflammation in mice.JOURNAL OF CLINICAL INVESTIGATION,2010
[8] mTOR Regulation and Therapeutic Rejuvenation of Aging Hematopoietic Stem Cells..Science Signaling,2009
[9] TSC-mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species..JOURNAL OF EXPERIMENTAL MEDICINE,2008