赖颖
所在单位：生物治疗全国重点实验室
职务：研究员
学历：博士研究生毕业
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Lai Y, Fois G, Flores JR, Tuvim MJ, Yang K, Zhou Q, Leitz J, Peters J, Zhang Y, Pfuetzner RA, Esquivies L, Jones P, Frick M, Dickey BF, Lai Y and Brunger AT.Inhibition of Ca2+-triggered secretion by hydrocarbon-stapled peptides.Nature,603:949-956,2022
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Du Y, Lai Y, Liu JY and Diao JJ.Epigenetic Quantification of DNA 5-Hydroxymethylcytosine U sing DNA Hybridization-Based Single-Molecule Immunofluorescent Imaging.Small methods,2021
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Brunger AT, Choi UB, Lai Y, Leitz J, Zhou Q and Brunger AT.Molecular mechanisms of fast neurotransmitter release.Annual review of biophysics,47:469-497,2018
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Lai Y, Choi UB, Leitz J, Rhee HJ, Lee C, Altas B, Zhao M, Pfuetzner RA, Wang AL, Brose N, Rhee J and Brunger AT.Molecular mechanisms of synaptic vesicle priming by Munc13 and Munc18.Neuron,95:591-607,2017
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Hu Y, Lai Y, Wang Y, Zhao M, Zhang Y, Crowe M, Tian Z, Long J and Diao J.SNARE‐Reconstituted Liposomes as Controllable Zeptoliter Nanoreactors for Macromolecules.Advanced Biosystems,1:2017
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Gong J, Lai Y, Li X, Wang M, Leitz J, Hu Y, Zhang Y, Choi UB, Cipriano DJ, Pfuetzner RA, Südhof TC, Yang X, Brunger AT and Diao J.The C-terminal domain of mammalian complexin-1 localizes to highly curved membranes.PNAS,113:E7590–7599,2016
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Lai Y, Choi UB, Zhang Y, Zhao M, Pfuetzner RA, Wang AL, Diao J and Brunger AT.N-terminal domain of complexin independently activates calcium-triggered fusion.PNAS,113:E4698-E4707,2016
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Lai Y, Lou X, Diao J and Shin YK.Molecular origins of synaptotagmin 1 activities on vesicle docking and fusion pore opening.Scientific Reports,5:2015
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Zhou Q, Lai Y, Bacaj T, Zhao M, Lyubimov A, Uervirojnangkoorn M, Zeldin O, Brewster A, Sauter N, Weis WI, Cohen A, Soltis S, Pfuetzner RA, Choi U, Diao J, Sudhof T and Brunger AT.Architecture of the synaptotagmin-SNARE machinery for neuronal exocytosis.Nature,525:62-67,2015
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Zhao Y, Lai Y, Bu B, Lou X, Li D, Ji B, Liu J, Diao J and Shin YK.Lipid molecules influence early stages of yeast SNARE-mediated membrane fusion.Physical biology,12:2015
