四川大学主页平台管理系统陈崇--中文主页--论文成果

个人信息

陈崇

正高

正高

电子邮箱：

入职时间：2014-09-03

所在单位：生物治疗全国重点实验室

职务：教授

在职信息：在岗

论文成果

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Mosaic loss of chromosome Y promotes leukemogenesis and clonal hematopoiesis.JCI Insight,2022.10.1172/jci.insight.153768
SRT1720 inhibits the growth of bladder cancer in organoids and murine models through the SIRT1-HIF axis.ONCOGENE,2021
An Epigenetic Mechanism Underlying Chromosome 17p Deletion–Driven Tumorigenesis.Cancer Discovery,2020
Deletions linked to TP53 loss drive cancer through p53-independent mechanisms.Nature,2016
MLL3 Is a Haploinsufficient 7q Tumor Suppressor in Acute Myeloid Leukemia.Cancer Cell,2014
Cancer-associated IDH2 mutants drive an acute myeloid leukemia that is susceptible to Brd4 inhibition.GENES & DEVELOPMENT,2013
Mammalian target of rapamycin activation underlies HSC defects in autoimmune disease and inflammation in mice.JOURNAL OF CLINICAL INVESTIGATION,2010
mTOR Regulation and Therapeutic Rejuvenation of Aging Hematopoietic Stem Cells..Science Signaling,2009
TSC-mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species..JOURNAL OF EXPERIMENTAL MEDICINE,2008

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